Increases in PGC-1α levels, similar to those that can be induced by physiological stimuli, altered intramuscular lipids and improved fatty acid oxidation, insulin signalling and insulin-stimulated glucose transport, albeit to different extents in lean and insulin-resistant muscle.
CiteULike: Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1α) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats: "Benton, C., Holloway, G., Han, X. X., Yoshida, Y., Snook, L., Lally, J., Glatz, J., Luiken, J., Chabowski, A., and Bonen, A. (2010). Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (pgc-1α) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese zucker rats. Diabetologia."
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